INGREDIENT RESEARCH

These ingredient summaries outline the intended use, safety, and effectiveness of dosage for all ingredients included in STUNN’s formulations. The intent is to provide scientific rational, research, safety data, and clinical studies to support the claims made for the intended use of STUNN’s products.

All ingredients are approved to be used in dietary supplements and dosages have been determined that are both safe and effective.

"Safe and effective dosing is an important consideration when it comes to supplementation. "

Although all ingredients are naturally derived, the quantity of each ingredient is crucial to the efficacy and safety of the formulation. For this reason, the clinical researched safe and effective dosage has been provided, and can be cross-referenced with the dosage used in our products.

If you have any questions regarding our research, terminology, or anything else, please feel free to reach out at [email protected]

AM YOUTH BOOST
INGREDIENT RESEARCH

Description: Gotu Kola is a natural, adaptogenic, aquatic botanical native to parts of Southeast Asia and India, and has been used in traditional medicine for over 3,000 years with modern supplementation dating back to the 19th century.

Alternate Names: Centella asiatica

Benefits:

  • Skin; Collagen, keratin, elasticity, hydration, cell repair
  • Mind; Cognition

How it works: The plant contains a host of bioactive natural compounds with a high abundance of triterpenoid saponins (i.e. centellosides), triterpenic acids, and glycosides. Recent research and clinical studies show active ingredients stimulate production of collagen and keratin, which support elasticity, hydration, tensile strength, and repair skin damage. Studies have also shown strong antioxidant and cognitive enhancing properties.

Safe and Effective Dosage: Research supports safe and effective dosages between 30-750 mg per day. 

Our dosage: 200 mg

Research/Reference [1,2]

Description: Polypodium leucotomos is a fern native to tropical regions of North and South America.  Traditionally used by the Native Americans, recent research indicates that it protects keratinocytes, which represent 90% of the cells in the epidermis or outer layer of the skin.

Alternate Names: Calaguala

Benefits:

  • Skin; Cellular regeneration, radiance, cell repair, UV protective

How it works: The plant contains a high abundance of glycosides that have demonstrated UV protective effects that help repair oxidative damage to the skin caused by sunlight exposure, supporting healthy cellular regeneration and radiance. Research has also shown potential induction of p53 proteins responsible for protecting DNA.

Safe and Effective Dosage: Research supports safe and effective dosages between 120-1080 mg per day.

Our dosage: 200 mg

Research/References: [3,4,5]

Description: Lycopene is a natural carotenoid found in vegetables and fruit, and is present in high amounts in tomatoes.

Alternate Names: N/A – the lycopene in AM YOUTH BOOST is from Tomato Extract

Benefits:

  • Skin; Radiance, hydration, UV protective

How it works: Studied extensively for over 70 years, lycopene has numerous health benefits, and like other carotenoids, is a powerful antioxidant and UV absorber. The compound also increases production of other carotenoids, such as beta-carotene. Carotenoids such as lycopene and beta-carotene are found in abundance in the skin and have photoprotective properties that protect cells from harmful UV radiation while supporting both radiance and hydration.

Safe and Effective Dosage: Clinical studies support safe dosages from 7 mg to over 75 mg per day, although recent research on bioavailability suggests the optimum dosage is 10 mg per day.

Dosage in AM YOUTH BOOST: 10 mg at a purity of 10% (this means the formulation contains 100 mg of tomato fruit extract, which contains 10 mg of lycopene)

Research/References: [6,7]

Description: Astaxanthin is found in most aquatic organisms with a red to pinkish color, and can be obtained naturally in abundance from microalgae (Haematococcus Pluvialis).

Alternate Names: N/A – the Astaxanthin used in AM YOUTH BOOST comes from a micro algae called Haematococcus Pluvialis. This is a vegan source of astaxanthin.

Benefits:

  • Skin; Cellular regeneration, radiance, UV protective, inflammation response
  • Body; Cardiovascular, joint support, inflammation response

How it works: A similar carotenoid with synergistic benefits to lycopene, Astaxanthin possesses a photoprotective UV structure, while providing additional benefits to healthy skin inflammation response, supporting cell regeneration, and promoting radiance of skin. Research has shown that Astaxanthin is beneficial for numerous other biological functions, such as cardiovascular and joint support. 

Safe and Effective Dosage: Clinical studies support safe dosages from 2 mg to over 25 mg per day, although recent research on bioavailability suggests a lower dose range of 2 mg per day as equally effective as elevated dosages.

Dosage in AM YOUTH BOOST: 2 mg at a purity of 1.5% (this means the formulation contains 134 mg of Haematococcus Pluvialis, which contains 2 mg of astaxanthin)

Research/References: [8,9]

Description: Ashwagandha is an adaptogenic plant that has been used for over 3,000 years in Ayurvedic medicine.

Alternate Names: Withania somnifera, Indian ginseng

Benefits:

  • Skin; Inflammation response, healthy aging
  • Mind; Stress reduction, cognition, focus, mood support
  • Body; Inflammation response

How it works: Primarily used to support resistance to stress by environmental conditions, the plant contains bioactive compounds called withanolides, which play a role in healthy aging and inflammation response, immune support, and maintaining homeostasis. 

Safe and Effective Dosage: Clinical research has shown that Ashwagandha supports cognition, focus, and mood response in individuals under chronic stress at dosages as low as 125 mg per day. Clinical studies support safe dosages from 125 mg to over 5 g per day. 

Our dosage: 150 mg

Research/References:[10,11,12]

Description: Boswellia serrata has been used for over 3,000 years in Ayurvedic medicine, and folk ceremonies that pre-date recorded history.

Alternate Names: Indian Frankincense

Benefits:

  • Mind; Stress reduction, cognition, focus, mood support
  • Body; Inflammation response

How it works: The gum of the plant contains resins and essential oils that are adaptogenic with strong synergistic mechanisms when combined with Ashwagandha. The most bioactive ingredient of the resin is acetyl-11-keto-β-boswellic acid (also known as AKBA) and is responsible for inhibition of pro-inflammatory enzymes, such as 5-lipoxygenase, which plays a crucial role in inflammatory processes throughout the body and brain. Through proper mediation of inflammation response, Boswellia allows the body to adjust to stress and to improve cognition and focus.

Safe and Effective Dosage: Clinical studies have shown safe and effective dosages between 50-600 mg, however, current research suggests the most effective dosage is 125 mg per day. 

Dosage in AM YOUTH BOOST: 125 mg

Research/References: [13,14,15]

Green Tea Leaf Extract

Description: Green tea has been studied extensively over the years, and is widely recognized for supporting longevity and health aging in Asian countries with regular consumption.

Alternate Names: N/A

Benefits:

  • Skin; Healthy aging, inflammation response
  • Body; Cardiovascular, inflammation response
  • Mind; Longevity, cognition

How it works: Green tea is high in bioactive polyphenols, such as the natural catechin known as ECGC. These have many targets within the body, with strong clinical research to support both cardiovascular health and a healthy inflammation response, two key indicators of longevity and healthy aging. Recent clinical studies have shown that polyphenols, such as ECGC, are capable of crossing the blood-brain barrier and provide neuroprotective effects that help with cognition during aging. 

Safe and Effective Dosage: Dosages and historic use have varied widely in research, with safe dosages of polyphenols over 4,000 mg per day. 

Dosage in AM YOUTH BOOST: 135 mg (44 mg polyphenols, 22 mg EGCG, 45 mg caffeine). This is  roughly equivalent to 1 cup of green tea. 

Research/References: [16,19,20]

Green Tea Leaf Extract – Caffeine

Description: Perhaps the most well studied and familiar compound, caffeine is a naturally occurring alkaloid found in several plant species, commonly in high abundance in tea leaves and coffee beans. Unlike synthetic versions, natural caffeine from green tea, delivers a slow, metered release of caffeine, and has natural synergistic ingredients like L-theanine that counteracts “jitters” or anxious feelings associated with caffeine intake.

Alternate Names: N/A

Benefits: 

  • Body; Sustainable energy
  • Mind; Stress reduction, cognition, focus

How it works: Caffeine stimulates the release of neurotransmitters and has been shown to aid in energy levels, cognition, focus, and reaction time, during presence of stress. 

Minimum effective Dosage: Clinical studies have shown safe doses of caffeine up to 400 mg per day, however, cognitive benefits can be shown as low as 20 mg.

Safe and Effective Dosage: 45 mg, roughly equivalent to 1 cup of tea. 

Research/References: [16,17,18]

Description: Acerola cherry is a natural fruit native to Central and South America.

Alternate Names: Malpighia emarginata, also known as Barbados cherry

Benefits:

  • Skin; Collagen, keratin, hydration, UV protective, 
  • Mind; Longevity, cognition

How it works: The fruit contains a natural abundance of Vitamin C, as well as other active compounds including flavonoids (such as quercetin) and polyphenols. Vitamin C is a well-known antioxidant for skin health that protects skin from UV rays, supports hydration, and plays a key role in collagen and keratin production. Recent research has shown that flavonoids and polyphenols derived from Acerola cherry fight harmful free radicals and inhibit advanced glycation end product (AGE) formation, which supports longevity and cognition during healthy aging.

Safe and Effective Dosage: Safe and effective dosages have been reported up to 1 g per day.

Dosage in AM YOUTH BOOST: 100 mg. The Acerola Cherry Extract used in AM YOUTH BOOST contains approximately 17 mg of natural Vitamin C and a complex blend of naturally active flavonoids and polyphenols.

Research/References: [21,22]

Description: Amla is native to India and is an adaptogenic plant that has been used for over 3,000 years in Ayurvedic medicine for its role in longevity and healthy aging.

Alternate Names: Phyllanthus emblica, also known as Indian Gooseberry

Benefits:

  • Skin; Hydration, tone and texture, healthy aging
  • Mind; Longevity, healthy aging

How it works: The plant contains high levels of natural bioactive compounds such as tannins, alkaloids, polyphenols, flavonoids, and Vitamin C. Containing a high natural abundance of low molecular tannins, research has shown that these compounds can promote healthy aging of the skin by reducing reactive oxygen species (ROS) that are responsible for photoaging, dryness and uneven pigmentation. The Amla fruit extract used in AM YOUTH BOOST is standardized to contain 40% natural tannins.

Safe and Effective Dosage: Amla fruit extracts and whole fruit have been used in clinical trials at safe and effective dosages up to 3 grams.

Dosage in AM YOUTH BOOST: 100 mg

Research/References: [23,24]

Description: Peppermint is a flowering plant in the mint family, that has historical use dating back to ancient Greece, Rome and Egypt civilizations.

Alternate Names: Mentha x piperita

Benefits:

  • Skin; Healthy aging, cell repair

How it works: Peppermint has historically been used as a tea, flavoring agent in foods, and an essential oil used for skin health in cosmetics. The plant contains a variety of bioactive compounds, such as rosmarinic acid and several flavonoids, primarily eriocitrin, luteolin and hesperidin. Recent research has shown that rosmarinic acid promotes healthy aging by increasing intracellular antioxidants and repairing damaged cells. 

Safe and Effective Dosage: Dosage is highly varied due to its use in concentrated oil, teas, and foods with safe dosage ranging up to 600 mg orally. 

Dosage in AM YOUTH BOOST: 100 mg

Research/References: [25,26]

PM CELL RESET
INGREDIENT RESEARCH

Description: Horsetail is a natural perennial plant widespread in the northern hemisphere, and native to North America, Russia, Norway, and Sweden.

Alternate Names: Equisetum arvense

Benefits:

  • Skin; Collagen, elasticity, strength,

How it works: The plant contains a wide variety of bioactive compounds known to support skin health, such as phytosterols, tannins, flavonoids, triterpenoids, and Vitamin C. Horsetail also contains a unique, natural form of silicon called salicylic acid. Silicon is essential for producing collagen and for the activation of enzymes within the collagen matrix that have been shown to support both skin strength and elasticity.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 10.5 mg to over 40 mg per day of Silica.

Dosage in PM CELL RESET: 200 mg. The Horsetail Stem Extract used in PM CELL RESET is standardized to 7% Silica, so the formulation contains approximately 14 mg of Silica.

Research/References: [27,28,29]

Description: Citrus Bioflavonoids represent a large number of natural plant polyphenols derived from the rinds and peels of citrus fruits such as grapefruit and oranges. Popular bioflavonoids include compounds such as quercetin, hesperidin, and rutin. 

Alternate Names: N/A

Benefits:

  • Skin; Elasticity, inflammation response, replenish aging cells, healthy aging
  • Mind; Longevity, healthy aging, cognition

How it works: Bioflavonoids have synergistic relationships with Vitamin C and have been shown to be powerful antioxidants that promote a healthy inflammation response during aging. Recent research has shown that flavonoids and polyphenols fight harmful free radicals and inhibit advanced glycation end product (AGE) formation, which supports longevity and cognition. Other studies have shown that flavonoids such as quercetin and rutin, can replenish aging cells, promoting elasticity and longevity of healthy skin.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 50 mg to over 500 mg per day. 

Dosage in PM CELL RESET: 100 mg

Research/References: [30,31,54,55]

Description: Lutein is a xanthophyll, or naturally occurring carotenoid, found in high quantities in the Marigold Flower. 

Alternate Names: Tagetes spp

Benefits:

  • Skin; Tone and texture, UV protective
  • Body; Eye health

How it works: Lutein is an essential component of the eye (e.g. lens/macula), but research has shown that it is also present in the skin, and is responsible for protection against UV induced damage caused by sunlight. Recent clinical studies have demonstrated that lutein is able to block melanin pathways, down regulate cytokines, and promote antioxidants, which promotes tone/texture improvements and improves skin appearance.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 6 mg to over 44 mg per day, with the optimal dose at 10 mg.

Dosage in PM CELL RESET: 10 mg at a purity of 5% (this means the formulation contains 200 mg of marigold flower extract, which contains 10 mg of Lutein)

Research/References: [33,34,35]

Description: Griffonia simplicifolia is a shrub native to Africa, whose seeds contain a high concentration of 5-hydroxytryptophan, otherwise known as 5-HTP. 

Alternate Names: N/A

Benefits:

  • Body; Sleep support
  • Mind; Serotonin increase, mood support

How it works: As a precursor to serotonin, 5-HTP increases serotonin, which triggers receptors in the central nervous system that modulate and support sleep and mood. Research has shown that serotonin is essential for bodyclock functions and regulation of sleep-wake behavior. Intended use is dependent on the time of day that serotonin levels are raised, therefore, 5-HTP is best supplemented in the afternoon to promote calm and a restful sleep. Valerian root, which contains GABA, is also synergistic with 5-HTP.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 55 mg to 900 mg per day, with our optimal dosage on the lower end of the range due to synergistic behavior with Valerian Root and Passion Flower.

Dosage in PM CELL RESET: 100 mg

Research/References: [36,37,38]

Description: Valerian is a flowering plant native to Europe and Asia, whose use dates back to ancient Greek and Roman civilizations.

Alternate Names: Valeriana officinalis

Benefits:

  • Body; Sleep support
  • Mind; Relaxation, promote calm

How it works: Valerian root is the most commonly used botanical to promote healthy sleep in the United States and Europe. The root of the plant has been shown to contain both gamma-aminobutyric acid (GABA) and bioactive compounds such as valerenic acid, which shows GABAergic activity. GABA is a neurotransmitter produced naturally in the body that is responsible for relaying messages through the brain and central nervous system to promote calm, relaxation, and healthy sleep without undesirable morning effects. 

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 100 mg to 600 mg per day with our optimal dosage on the lower end of the range due to synergistic behavior with 5-HTP from Griffonia simplicifolia and Passion Flower.

Dosage in PM CELL RESET: 200 mg

Research/References: [38,39,40,41,42,43]

Description: Passion Flower is a perennial climbing vine, native to tropical regions of North, Central, and Southern America. Historical usage of the plant dates back to Native Americans and the Aztecs, as well as modern cultures, with the primary use related to calming and promoting sleep.

Alternate Names: Passiflora incarnata

Benefits:

  • Body; Sleep support
  • Mind; Relaxation, promote calm, stress reduction

How it works: The flower of this plant contains a vast array of bioactive compounds such as flavonoids, glycosides, and amino acids, including GABA. Synergistic with both Griffonia simplicifolia and Valerian Root due to its role in GABAergic activity, research also supports its use to promote quality of life for restlessness and stress.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 50 mg to over 700 mg per day, with our optimal dosage on the lower end of the range due to synergistic behavior with 5-HTP from Griffonia simplicifolia and Valerian Root.

Dosage in PM CELL RESET: 75 mg

Research/References: [30,51,52]

Description: Lavender Flower is a flowering plant in the mint family with documented use for over 2,500 years, extending back to ancient Egypt.

Alternate Names: Lavandula spp.

Benefits: 

  • Skin; Healthy aging
  • Body; Sleep support
  • Mind; Relaxation, promote calm

How it works: Used in cooking, essential oils, and perfumes, recent research has shown beneficial results used both orally and topically to promote healthy aging of skin and body through interactions with prostanoids, proinflammatory cytokines, and histamine pathways. Clinical research supports the use of lavender to promote natural, healthy stress response, sleep quality, and relaxation.

Safe and Effective Dosage: Dosage is highly varied due to its use in concentrated oil, teas, and foods, with dosage ranging from 80 mg to over 1000 mg.

Dosage in PM CELL RESET: 200 mg

Research/References: [46,47]

Description: Hops Flower is a member of the Cannabaceae family (which includes hemp and hackberries) and is a natural plant originating in China and widely cultivated for its use in supplements and beer.

Alternate Names: Humulus lupulus

Benefits:

  • Skin; Healthy aging, cell regeneration
  • Body; Sleep support, longevity, healthy aging, cholesterol 
  • Mind; Relaxation, promote calm, mood support, stress reduction

How it works: Although it is widely researched and cultivated for its bitter acids used in beer making, hops also contains oil terpenoids such as mycerne, beta-caryophyllene, and a complex mixture of flavonoids and polyphenols, which benefit skin health. Hops have long been used with valerian root, and have a synergistic relationship to promote mood and support healthy stress response. Recent research has also shown that natural terpenoids help maintain healthy cholesterol levels and scavenge harmful hydroxyl free radicals, essential to healthy aging and longevity.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 60 mg to over 200 mg per day.

Dosage in PM CELL RESET: 125 mg

Research/References: [48,49,50]

Description: Japanese Knotweed is a dense growing shrub native to Eastern Asia, and introduced into North America in the late 1800s. 

Alternate Names: Polygonum cuspidatum

Benefits:

  • Skin; Cell repair, healthy aging
  • Body; Longevity, healthy aging, cardiovascular

How it works: The plant extract is popular in both historical and modern use for its high natural abundance of trans-resveratrol, a natural phenol well studied for its support of cardiovascular health, skin health, longevity, and healthy aging. Studies have shown that resveratrol targets active sites in epidermal cells and can upregulate compounds within the body (i.e. glutathione peroxidase) that protect against oxidative related skin damage during aging.

Safe and Effective Dosage: Clinical studies support safe and effective dosages of between 1 to 1000 mg, with most beneficial dosage at 20 mg.

Dosage in PM CELL RESET: 20 mg

Research/References:  [30,51,52,53]

PM CELL RESET
INGREDIENT RESEARCH

Description: Horsetail is a natural perennial plant widespread in the northern hemisphere, and native to North America, Russia, Norway, and Sweden.

Alternate Names: Equisetum arvense

Benefits:

  • Skin; Collagen, elasticity, strength,

How it works: The plant contains a wide variety of bioactive compounds known to support skin health, such as phytosterols, tannins, flavonoids, triterpenoids, and Vitamin C. Horsetail also contains a unique, natural form of silicon called salicylic acid. Silicon is essential for producing collagen and for the activation of enzymes within the collagen matrix that have been shown to support both skin strength and elasticity.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 10.5 mg to over 40 mg per day of Silica.

Dosage in PM CELL RESET: 200 mg. The Horsetail Stem Extract used in PM CELL RESET is standardized to 7% Silica, so the formulation contains approximately 14 mg of Silica.

Research/References: [27,28,29]

Description: Citrus Bioflavonoids represent a large number of natural plant polyphenols derived from the rinds and peels of citrus fruits such as grapefruit and oranges. Popular bioflavonoids include compounds such as quercetin, hesperidin, and rutin. 

Alternate Names: N/A

Benefits:

  • Skin; Elasticity, inflammation response, replenish aging cells, healthy aging
  • Mind; Longevity, healthy aging, cognition

How it works: Bioflavonoids have synergistic relationships with Vitamin C and have been shown to be powerful antioxidants that promote a healthy inflammation response during aging. Recent research has shown that flavonoids and polyphenols fight harmful free radicals and inhibit advanced glycation end product (AGE) formation, which supports longevity and cognition. Other studies have shown that flavonoids such as quercetin and rutin, can replenish aging cells, promoting elasticity and longevity of healthy skin.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 50 mg to over 500 mg per day. 

Dosage in PM CELL RESET: 100 mg

Research/References: [30,31,54,55]

Description: Lutein is a xanthophyll, or naturally occurring carotenoid, found in high quantities in the Marigold Flower. 

Alternate Names: Tagetes spp

Benefits:

  • Skin; Tone and texture, UV protective
  • Body; Eye health

How it works: Lutein is an essential component of the eye (e.g. lens/macula), but research has shown that it is also present in the skin, and is responsible for protection against UV induced damage caused by sunlight. Recent clinical studies have demonstrated that lutein is able to block melanin pathways, down regulate cytokines, and promote antioxidants, which promotes tone/texture improvements and improves skin appearance.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 6 mg to over 44 mg per day, with the optimal dose at 10 mg.

Dosage in PM CELL RESET: 10 mg at a purity of 5% (this means the formulation contains 200 mg of marigold flower extract, which contains 10 mg of Lutein)

Research/References: [33,34,35]

Description: Griffonia simplicifolia is a shrub native to Africa, whose seeds contain a high concentration of 5-hydroxytryptophan, otherwise known as 5-HTP. 

Alternate Names: N/A

Benefits:

  • Body; Sleep support
  • Mind; Serotonin increase, mood support

How it works: As a precursor to serotonin, 5-HTP increases serotonin, which triggers receptors in the central nervous system that modulate and support sleep and mood. Research has shown that serotonin is essential for bodyclock functions and regulation of sleep-wake behavior. Intended use is dependent on the time of day that serotonin levels are raised, therefore, 5-HTP is best supplemented in the afternoon to promote calm and a restful sleep. Valerian root, which contains GABA, is also synergistic with 5-HTP.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 55 mg to 900 mg per day, with our optimal dosage on the lower end of the range due to synergistic behavior with Valerian Root and Passion Flower.

Dosage in PM CELL RESET: 100 mg

Research/References: [36,37,38]

Description: Valerian is a flowering plant native to Europe and Asia, whose use dates back to ancient Greek and Roman civilizations.

Alternate Names: Valeriana officinalis

Benefits:

  • Body; Sleep support
  • Mind; Relaxation, promote calm

How it works: Valerian root is the most commonly used botanical to promote healthy sleep in the United States and Europe. The root of the plant has been shown to contain both gamma-aminobutyric acid (GABA) and bioactive compounds such as valerenic acid, which shows GABAergic activity. GABA is a neurotransmitter produced naturally in the body that is responsible for relaying messages through the brain and central nervous system to promote calm, relaxation, and healthy sleep without undesirable morning effects. 

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 100 mg to 600 mg per day with our optimal dosage on the lower end of the range due to synergistic behavior with 5-HTP from Griffonia simplicifolia and Passion Flower.

Dosage in PM CELL RESET: 200 mg

Research/References: [38,39,40,41,42,43]

Description: Passion Flower is a perennial climbing vine, native to tropical regions of North, Central, and Southern America. Historical usage of the plant dates back to Native Americans and the Aztecs, as well as modern cultures, with the primary use related to calming and promoting sleep.

Alternate Names: Passiflora incarnata

Benefits:

  • Body; Sleep support
  • Mind; Relaxation, promote calm, stress reduction

How it works: The flower of this plant contains a vast array of bioactive compounds such as flavonoids, glycosides, and amino acids, including GABA. Synergistic with both Griffonia simplicifolia and Valerian Root due to its role in GABAergic activity, research also supports its use to promote quality of life for restlessness and stress.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 50 mg to over 700 mg per day, with our optimal dosage on the lower end of the range due to synergistic behavior with 5-HTP from Griffonia simplicifolia and Valerian Root.

Dosage in PM CELL RESET: 75 mg

Research/References: [30,51,52]

Description: Lavender Flower is a flowering plant in the mint family with documented use for over 2,500 years, extending back to ancient Egypt.

Alternate Names: Lavandula spp.

Benefits: 

  • Skin; Healthy aging
  • Body; Sleep support
  • Mind; Relaxation, promote calm

How it works: Used in cooking, essential oils, and perfumes, recent research has shown beneficial results used both orally and topically to promote healthy aging of skin and body through interactions with prostanoids, proinflammatory cytokines, and histamine pathways. Clinical research supports the use of lavender to promote natural, healthy stress response, sleep quality, and relaxation.

Safe and Effective Dosage: Dosage is highly varied due to its use in concentrated oil, teas, and foods, with dosage ranging from 80 mg to over 1000 mg.

Dosage in PM CELL RESET: 200 mg

Research/References: [46,47]

Description: Hops Flower is a member of the Cannabaceae family (which includes hemp and hackberries) and is a natural plant originating in China and widely cultivated for its use in supplements and beer.

Alternate Names: Humulus lupulus

Benefits:

  • Skin; Healthy aging, cell regeneration
  • Body; Sleep support, longevity, healthy aging, cholesterol 
  • Mind; Relaxation, promote calm, mood support, stress reduction

How it works: Although it is widely researched and cultivated for its bitter acids used in beer making, hops also contains oil terpenoids such as mycerne, beta-caryophyllene, and a complex mixture of flavonoids and polyphenols, which benefit skin health. Hops have long been used with valerian root, and have a synergistic relationship to promote mood and support healthy stress response. Recent research has also shown that natural terpenoids help maintain healthy cholesterol levels and scavenge harmful hydroxyl free radicals, essential to healthy aging and longevity.

Safe and Effective Dosage: Clinical studies support safe, effective dosages between 60 mg to over 200 mg per day.

Dosage in PM CELL RESET: 125 mg

Research/References: [48,49,50]

Description: Japanese Knotweed is a dense growing shrub native to Eastern Asia, and introduced into North America in the late 1800s. 

Alternate Names: Polygonum cuspidatum

Benefits:

  • Skin; Cell repair, healthy aging
  • Body; Longevity, healthy aging, cardiovascular

How it works: The plant extract is popular in both historical and modern use for its high natural abundance of trans-resveratrol, a natural phenol well studied for its support of cardiovascular health, skin health, longevity, and healthy aging. Studies have shown that resveratrol targets active sites in epidermal cells and can upregulate compounds within the body (i.e. glutathione peroxidase) that protect against oxidative related skin damage during aging.

Safe and Effective Dosage: Clinical studies support safe and effective dosages of between 1 to 1000 mg, with most beneficial dosage at 20 mg.

Dosage in PM CELL RESET: 20 mg

Research/References:  [30,51,52,53]

TERMINOLOGY

Minimum Effective Dosage

A minimum effective dose refers to the minimum amount of an ingredient required for an intended benefit.

Safe dosage

Most ingredients have a clinically researched dosage threshold, whereby when crossed, the ingredient becomes toxic. The safe dosage refers to the clinically studied dosage limits that are safe for regular consumption.

Bioavailability

Bioavailability refers to the proportion of the nutrient that is absorbed through normal pathways

Adaptogen

Adaptogens are natural substances (sometimes referred to as herbal pharmaceuticals) considered to help the body adapt to stress and to exert a normalizing effect upon bodily processes.

Adaptogens have many benefits, including neuroprotective elements, anti-fatigue properties, antidepressive effects, they stimulate the central nervous system, and they increase mental work capacity, enhance attention, and prevent stress and fatigue.

AM YOUTH BOOST contains a variety of adaptogenic plants, including Gotu Kola, Ashwagandha, Boswellia Serrata, Amla Fruit. They are beneficial for use in the morning for their calming but energizing effects, and for their ability to help you manage stressors throughout the day.

Whole fruit (powder) vs. Extract

Natural plant ingredients can be used either as a whole fruit (powder), or as an extract. Extracts are often used to help isolate a specific, key compound in the plant, which provides a standardized ingredient.

Though extracts are standardized for specific compounds, there are times when a whole fruit (powder) is preferable, as all natural plant ingredients contain a variety of compounds with synergistic benefits, and extracting out key compounds may not serve the intended benefit as optimally.

Synergistic effects

Synergy in nutritional supplements refers to the combined effect of the individual ingredients – a sum which is more powerful than the sum of the individual ingredients by themselves. With natural plant ingredients, the synergistic effects are quite complex, and must be evaluated extensively when creating quality formulation. Some ingredients enhance the effectiveness of each other, while others cancel out certain effects when they are used together.

Ingredient synergies must be considered to ensure the proper dosing of ingredients is used, and to ensure the intended effects are present.

STUNN Collective has extensively researched the synergistic effects of ingredient combinations present in AM YOUTH BOOST and PM CELL RESET to ensure proper dosing and desired effects.

Antioxidant

Antioxidants are molecules that fight free radicals in your body and are known for their ability to prevent, and in some cases, reverse cellular damage. For more information on antioxidants and free radicals, check out the following articles:

https://www.stunnco.com/three-of-the-best-antioxidants-for-your-skin/

https://www.stunnco.com/how-to-prevent-collagen-loss-and-repair-damaged-cells/

Botanical

From the National Institute of Health, a botanical is a plant or plant part valued for its medicinal or therapeutic properties, flavor, and/or scent. Herbs are a subset of botanicals. Products made from botanicals that are used to maintain or improve health may be called herbal products, botanical products, or phytomedicines. Both AM YOUTH BOOST and PM CELL RESET contain a variety of botanical ingredients.

Free Radicals

Free radicals are highly unstable and reactive waste molecules produced by cells as the body processes foods and reacts to the environment. For more information on antioxidants and free radicals, check out the following articles:


https://www.stunnco.com/three-of-the-best-antioxidants-for-your-skin/

https://www.stunnco.com/how-to-prevent-collagen-loss-and-repair-damaged-cells/

Polyphenol

Polyphenols are a category of compound commonly found in plants that act as antioxidants.

Carotenoid

Carotenoids are pigments commonly found in plants that act as antioxidants. These pigments produce red, yellow, and orange colors in plants, fruits and vegetables. Lycopene, Astaxanthin, and Lutein are all carotenoids.

Flavonoids

Flavonoids are a type of polyphenol responsible for giving plants vivid colors. They are rich in antioxidants, and are found in many plants.

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