GRIFFONIA SIMPLICIFOLIA

Ultimate pm - 100mg

Griffonia simplicifolia is a shrub native to Africa, whose seeds contain a high concentration of 5-hydroxytryptophan, otherwise known as 5-HTP.

HOW IT WORKS

As a precursor to serotonin, 5-HTP increases serotonin, which triggers receptors in the central nervous system that modulate and support sleep and mood. Research has shown that serotonin is essential for bodyclock functions and regulation of sleep-wake behavior. Intended use is dependent on the time of day that serotonin levels are raised, therefore, 5-HTP is best supplemented in the afternoon to promote calm and a restful sleep. Valerian root, which contains GABA, is also synergistic with 5-HTP.

BENEFITS

Naturally increase serotonin
 Improve mood
  Support gut health

Improve cognition
Promote calm
 Support quality sleep

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RESEARCH &
CLINICAL STUDIES

"Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis"

An influence of gut microbiota on behaviour is becoming increasingly evident, as is the extension to effects on tryptophan and serotonin metabolism.

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"Sleep-promoting effects of a GABA/5-HTP mixture: Behavioral changes and neuromodulation in an invertebrate model"

In this regard, we successfully demonstrated that using a GABA/5-HTP mixture modulates subjective nighttime activity, sleep episodes, and total duration of subjective nighttime sleep to a greater extent than single administration of each amino acid, and that this modulation occurs via GABAergic and serotonergic signaling.

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"5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology"

The main application of 5-HTP is as a support for serotonin depletion and is considered an interesting alternative to the use of SSRIs. 

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VIEW MORE INGREDIENTS

Valerian is a flowering plant native to Europe and Asia, whose use dates back to ancient Greek and Roman civilizations.

Dosage: 200mg

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Passion Flower is a perennial climbing vine, native to tropical regions of North, Central, and Southern America.

Dosage: 75mg

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Citrus Bioflavonoids represent a large number of natural plant polyphenols derived from the rinds and peels of citrus fruits such as grapefruit and oranges.

Dosage: 100mg

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Passion Flower is a perennial climbing vine, native to tropical regions of North, Central, and Southern America.

Dosage: 75mg

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Japanese Knotweed (Resveratrol) is a dense growing shrub native to Eastern Asia, and introduced into North America in the late 1800s.

Dosage: 20mg

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