Haematococcus Pluvialis(micro algae)
Astaxanthin is found in most aquatic organisms with a red to pinkish color, and can be obtained naturally in abundance from microalgae (Haematococcus Pluvialis).
✓ Amplify radiance
✓ Activate cellular regeneration
✓ UV protective benefits
✓ Support healthy inflammation response
✓ Support cardiovascular health
✓ Supports joint health
How it works:
A similar carotenoid with synergistic benefits to lycopene, Astaxanthin possesses a photoprotective UV structure, while providing additional benefits to healthy skin inflammation response, supporting cell regeneration, and promoting radiance of skin. Research has shown that Astaxanthin is beneficial for numerous other biological functions, such as cardiovascular and joint support.
Safe and Effective Dosage:
Clinical studies support safe dosages from 2 mg to over 25 mg per day, although recent research on bioavailability suggests a lower dose range of 2 mg per day as equally effective as elevated dosages.
2 mg at a purity of 1.5% (this means the formulation contains 134 mg of Haematococcus Pluvialis, which contains 2 mg of astaxanthin).
RESEARCH &CLINICAL STUDIES
"Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review"
Astaxanthin, a xanthophyll carotenoid, is a secondary metabolite naturally synthesized by a number of bacteria, microalgae, and yeasts.
The commercial production of this pigment has traditionally been performed by chemical synthesis, but the microalga Haematococcus pluvialis appears to be the most promising source for its industrial biological production.
Due to its collective diverse functions in skin biology, there is mounting evidence that astaxanthin possesses various health benefits and important nutraceutical applications in the field of dermatology.
Although still debated, a range of potential mechanisms through which astaxanthin might exert its benefits on skin homeostasis have been proposed, including photoprotective, antioxidant, and anti-inflammatory effects.
This review summarizes the available data on the functional role of astaxanthin in skin physiology, outlines potential mechanisms involved in the response to astaxanthin, and highlights the potential clinical implications associated with its consumption.
"Protective effects of Astaxanthin on skin deterioration"
Astaxanthin is a carotenoid with potent antioxidant and anti-inflammatory activity. To evaluate the anti-inflammatory effect of astaxanthin on skin deterioration, we confirmed its role in epidermal-dermal interactions in vitro.
Astaxanthin treatment suppressed ultraviolet B (UVB)-induced inflammatory cytokine secretion in keratinocytes, and matrix metalloproteinase-1 secretion by fibroblasts cultured in UVB-irradiated keratinocyte medium. To verify these findings, we conducted a 16-week clinical study with 65 healthy female participants.
Participants were orally administered either a 6 mg or 12 mg dose of astaxanthin or a placebo. Wrinkle parameters and skin moisture content significantly worsened in the placebo group after 16 weeks. However, significant changes did not occur in the astaxanthin groups.
Interleukin-1α levels in the stratum corneum significantly increased in the placebo and low-dose groups but not in the high-dose group between weeks 0 and 16. This study was performed in Japan from August to December, when changing environmental factors, such as UV and dryness, exacerbate skin deterioration.
In conclusion, our study suggests that long-term prophylactic astaxanthin supplementation may inhibit age-related skin deterioration and maintain skin conditions associated with environmentally induced damage via its anti-inflammatory effect. (UMIN Clinical Trials Registry ID: UMIN000018550)